Susana R. Louros, PhD

Postdoctoral fellow

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Centre for Discovery Brain Sciences

University of Edinburgh

Hugh Robson Building, George Square

Edinburgh, EH8 9XD

Email:

Education and Academic Positions

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• Postdoctoral Fellow, Centre for Discovery Brain Sciences, University of Edinburgh

• Postdoctoral Fellow, Center for Neuroscience and Cell Biology, University of Coimbra, Portugal

• Ph.D. in Biology (Magna cum laude), University of Coimbra, Portugal

• Bachelor Diploma in Biology, University of Coimbra, Portugal

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Support

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• Portuguese Science Foundation - FCT: PI Susana Louros. Title: A role for Contactin-associated proteins 1 and 2 in experience-dependent plasticity: PTDC/NEU-NMC/4888/2014 - amount € 199,430

• PhD scholarship from the Portuguese Foundation for Science and Technology

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Publications

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• Muscas, M., Louros, S. R. and Osterweil, E.K. Lovastatin, not simvastatin, corrects core phenotypes in a mouse model of Fragile X Syndrome. eNeuro. In press.

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• Asiminas, A.*, Jackson, A. D.*, Louros, S.†, Till, S. M.†, Spano, T., Dando, O., Bear, M. F., Chattarji, S., Hardingham, G. E., Osterweil, E. K., Wyllie, D. J. A., Wood, E. R., Kind, P. C. Sustained correction of associative learning deficits following brief, early treatment in a rat model of Fragile X Syndrome. Science Translational Medicine. In press.

*,✝ authors contributed equally

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• Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses. Louros SR, Caldeira GL, Carvalho AL. Front Mol Neurosci. 2018 Sep 13;11:328. doi: 10.3389/fnmol.2018.00328. eCollection 2018.

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• Thomson, S. R.*, Seo, S. S.*, Barnes, S. A.✝, Louros, S. R.✝, Muscas, M., Dando, O., Kirby, C., Hardingham, G. E., Wyllie, D. J. A., Kind, P. C., and Osterweil, E. K. Cell type-specific translation profiling reveals a novel strategy for treating fragile X syndrome. Neuron. 2017 Aug 2; 95(3):550-563.e5. doi: 10.1016/j.neuron.2017.07.013.

*,✝ authors contributed equally

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• Louros, S. R., Osterweil, E. K.  Perturbed proteostasis in autism spectrum disorders. Journal of Neurochemistry. 2016 Dec;139(6):1081-1092. doi: 10.1111/jnc.13723. Epub 2016 Aug 4.

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• Matos CA, Nóbrega C*, Louros SR*, Almeida B✝, Ferreiro E, Valero J, Pereira de Almeida L, Macedo-Ribeiro S, Carvalho AL. Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models. J Cell Biol. 2016 Feb 15;212(4):465-80. doi: 10.1083/jcb.201506025.

* authors contributed equally

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• Louros SR, Hooks BM, Litvina L, Carvalho AL and Chen C. A role for stargazin in experience-dependent plasticity. Cell Reports. 2014; 7(5): 1614-1625.

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• Rosenstock TR, Brito OM, Lombardi V, Louros S, Ribeiro M, Almeida S, Ferreira IL, Oliveira CR, Rego AC. FK506 ameliorates cell death features in Huntington’s disease striatal cell models. Neurochemistry International, 2011 Oct; 59(5):600-9.

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