Sophie R. Thomson, PhD

Postdoctoral fellow

Centre for Integrative Physiology

University of Edinburgh

Hugh Robson Building, George Square

Edinburgh, EH8 9XD


Academic positions

  • Postdoctoral Fellow, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK




  • Ph.D. in Neuroscience 2013, University of Edinburgh

  • B.Sc (Hons) Neuroscience 2010, University of Edinburgh

Research Support

  • Tuberous Sclerosis Association, Postdoctoral Fellowship, PI: Sophie Thomson (Supervisor: Emily Osterweil). Title: Targeting the mGluR5-FMRP signaling pathway for the treatment of TSC. Amount: £153,971


  • Thomson, S. R.*, Seo, S. S.*, Barnes, S. A.✝, Louros, S. R.✝, Muscas, M., Dando, O., Kirby, C., Hardingham, G. E., Wyllie, D. J. A., Kind, P. C., Osterweil, E. K. Cell type-specific translation profiling reveals a novel strategy for treating fragile X syndrome. Neuron. In press.

*,✝ authors contributed equally


  • Boyd PJ, Tu WY, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy.  PLoS Genet. 2017. 13(4):e1006744

  • Thomson SR, Nahon JE, Mutsaers CA, Thomson D, Hamilton G, Parson SH, Gillingwater TH. Morphological characteristics of motor neurons do not determine their relative susceptibility to degeneration in a mouse model of severe spinal muscular atrophy. PLoS One. 2013. 7(12):e52605

  • Thomson SR, Wishart TM, Patani R, Chandran S, Gillingwater TH. Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality? J. Anat. 2012. 220(2):122-30.

  • Osterlab

Osterweil Lab,

University of Edinburgh